![]() ![]() Therefore, the inclusion of personality measures to study the link between the digit ratio and schizophrenia might help to provide insights in a potential continuum from healthy to schizophrenic behavior.ĭigit ratio Personality SPQ Schizophrenia.Ĭopyright © 2014 Elsevier B.V. Same results were observed for the digit ratio of the left hand and the SPQ in the healthy total and healthy female subsample. However, a positive association between right 2D:4D ratio and schizotypal personality traits was found in healthy controls (both in the male and female subsamples) suggesting that a high 2D:4D ratio could represent a vulnerability factor for schizophrenia in healthy males and females. No significant difference between cases and controls in 2D:4D ratios for both hands could be observed. ![]() Moreover, we investigated the link between 2D:4D ratios and schizotypal personality traits in the participants of the study. The ratios of 2D:4D between 0.96 and 1.01 of both hands associated with an increased risk of. Conclusion: The ratios of 2D:4D of both hands of autistic children were lower corrected than non-autistic children. In the current study, we tried to replicate the result of this study on the 2D:4D ratio in schizophrenia patients and controls in a Chinese sample. The 2D:4D ratio of both hands between 0.96 and 1.01 were risk factors of autism with odds ratio between 3.22 and 5.35 (p < 0.05). (2010) examined 2D:4D ratios in Asian patients with schizophrenia and found an increased 2D:4D pattern in male patients compared to male healthy controls. In this context, the ratio of the index finger to ring finger length (2D:4D) has been put forward as an indicator of the intrauterine sex hormonal level. Prenatal estrogen/testosterone exposure is known to be involved in early brain development. ![]()
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